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GPVI non-covalently associates with the signal-transducing FcR gamma-chain and serves as an activating collagen receptor.PriceCloneIsotypeForm ApplicationsSizeCat.No.USDJAQ1 Rat IgG2apurif. IP, IHC, WB0.1 mgM011-0FITCFC, IHC1.5 ml; 300 testsM011-1.Integrin alphaIIbbeta3 (GPIIb/IIIa, CD41/CD61)Integrin alpha IIb beta 3 is a platelet/megakaryocyte-specific receptor for a number of ligands, including von Willebrand factor (vWf), fibrinogen, fibronectin, and vitronectin.Leo.F2IP, IHC0.5 mgM025-0M025-1PEM025-2 DyLight 649M025-3Leo.H4 Rat IgG2bIP, IHC, blockM021-0M021-1Leo.A1Rat IgG1M022-0JON/AFC (activ. form)M023-2Integrin alphaIIb (GPIIb, CD41)Integrin alphaIIb non-covalently associates with the beta3 chain to form the integrin alphaIIb beta3 (GPIIbIIIa). Integrin alphaIIbbeta3 is a platelet receptor for fibrinogen, von Willebrand factor, fibronectin, and vitronectin and it mediates platelet adhesion and aggregation.MwReg30$IP, IHC, generation of Fab fragments6 mgM024-07Integrin beta3 chain (GPIIIa, CD61) mouse and humanThe integrin beta 3 chain non-covalently associates with the alpha IIb chain to form the integrin alpha IIb beta3 in platelets or with the alpha v chain to form the integrin alpha v beta3 in platelets, endothelial cells and other cell types.Luc.A5M030-0Luc.H11M031-0M031-1GPIbalpha (CD42b)GPIb alpha is part of the GPIb-V-IX complex, the platelet receptor for von Willebrand factor (vWf). GPIb alpha is proteolytically cleaved during platelet activation.Xia.G5M040-0M040-1M040-2M040-3Xia.H10M041-0M041-1Xia.G7M042-0M042-1Xia.B2M043-0M043-1 GPIbbeta (CD42c) mouse and humanGPIb beta is part of the GPIb-V-IX complex, the platelet receptor for von Willebrand factor (vWf). GPIb beta is disulfide-linked with GPIb alpha in the membrane.Xia.C3M050-0M050-1 GPIX (CD42a)GPIX is part of the GPIb-V-IX complex, the platelet receptor for von Willebrand factor (vWf). GPIX is non-covalently associated with GPIb alpha/beta.Xia.B4M051-0M051-1 GPV (CD42d)GPV non-covalently associates with the GPIb-IX complex and has been reported to be a low-affinity collagen receptor. GPV is proteolytically cleaved by thrombin.Gon.C2M060-1Gon.G6M061-1#Integrin alpha2 chain (CD49b, GPIa)The integrin alpha 2 chain non-covalently associates with the integrin beta 1 subunit to form the integrin alpha 2 beta 1 known as VLA-2. Integrin alpha 2 beta 1 is a receptor for collagen and laminin.Sam.G4M070-0M070-1Sam.C1M071-0M071-1-Integrin alpha5 chain (CD49e) mouse and humanThe integrin alpha 5 chain non-covalently associates with the integrin beta 1 subunit to form the alpha 5 beta 1 complex, a receptor for fibronectin that is widely expressed in tissue and to a lower extent on platelets. Tap.A12M080-0M080-1CD9CD9 is a single chain surface glycoprotein that is involved in cell adhesion, cell migration, and integrin signaling. CD9 is expressed on platelets, many leukocytes, and widely in the tissue.Nyn.H3M110-0M110-1CD31 (PECAM-1)PECAM-1 is an integral membrane glycoprotein for cell adhesion that is expressed constitutively on the surface of endothelial cells and to lower extent on platelets and many leukocytes.Pec.H3M120-0CD62P (P-selectin)P-selectin is an adhesion molecule stored in alpha-granules of platelets and Weibel Palade bodies of endothelial cells. Upon cellular activation, P-selectin is translocated to the surface membrane.Wug.E9M130-0M130-1M130-2von Willebrand Factor (vWF)vWf is a multimeric plasma protein that is also stored intracellularly in platelets and endothelial cells and is released upon activation. The interaction between vWf and its receptor GPIb alpha can be induced by the snake venom protein botrocetin. polyclonal Rabbit IgGP150-1 fibrinogenFibrinogen is a plasma protein that is also found in alpha-granules of platelets that is essential for hemostasis as it mediates platelet<  aggregation and blood coagulation.P140-1negative control1.0 ml; 200 testsP180-1Rat IgGP190-1P190-2P190-3'Antibodies for Mouse Platelet DepletionfThis antibody preparation induces profound and irreversible Fc-independent platelet depletion in mice.purifiedplatelet depletionR300anti-GPIb alpha non-immunecontrol for #R300C301/Two-Color Analysis of Mouse Platelet ActivationThis product provides a ready-to-use tool to determine integrin alpha IIb beta 3 (GPIIb/IIIa) activation and alpha-granule secretion (P-selectin expression) of mouse platelets by flow cytometry.flow cytometry1 ml; 200 testsD200In Vivo Mouse Platelet Labeling8Antibody preparation for in Vivo Mouse Platelet Labelinganti - GPIbbeta derivative DyLight 488in vivo platelet labelingX488X649'ST TĉCD9CloneNyn.H3 IsotypeRat IgG2a hFITC ApplicationsFC, IHCNCD31 (PECAM-1)ClonePec.H3 IsotypeRat IgG1 hpurif. ApplicationsIP, IHC, WBNCD62P (P-selectin)CloneWug.E9 IsotypeRat IgG1 hpurif. ApplicationsIP, IHCLCD62P (P-selectin)CloneWug.E9 IsotypeRat IgG1 hFITC ApplicationsFC, IHCJCD62P (P-selectin)CloneWug.E9 IsotypeRat IgG1 hPE ApplicationsFC, IHC[von Willebrand Factor (vWF)Clonepolyclonal IsotypeRabbit IgG hFITC ApplicationsFC, IHCJfibrinogenClonepolyclonal IsotypeRabbit IgG hFITC ApplicationsFC, IHCPnegative controlClonepolyclonal IsotypeRabbit IgG hFITC ApplicationsFC, IHCMnegative controlClonepolyclonal IsotypeRat IgG hFITC ApplicationsFC, IHCKnegative controlClonepolyclonal IsotypeRat IgG hPE ApplicationsFC, IHCTnegative controlClonepolyclonal IsotypeRat IgG hDyLight 649 ApplicationsFC, IHCxAntibodies for Mouse Platelet DepletionCloneanti-GPIb alpha IsotypeRat IgG hpurified Applicationsplatelet depletionrAntibodies for Mouse Platelet DepletionClonenon-immune IsotypeRat IgG hpurified Applicationscontrol for #R300pTwo-Color Analysis of Mouse Platelet ActivationCloneWug.E9 IsotypeRat IgG1 hFITC Applicationsflow cytometryIn Vivo Mouse Platelet LabelingCloneanti - GPIbbeta derivative IsotypeRat IgG hDyLight 488 Applicationsin vivo platelet labelinglIn Vivo Mouse Platelet LabelingCloneanti - GPIbbeta derivative IsotypeRat IgG hDyLight 649 Applications WA    b%Ӟi߾  dMbP?_*+%&HzG?'HzG?(\(\?)\(\?" dX\(\?\(\?&U} W} "} I} m X} m Y} m Zb   @    @           @   @     @        [ [\\\\] ^ _````a b^ c c c c c d e ^ f f g h h i~ jpw@ kll m m m \~ n}@ ^ _````a b^ c c c c c d o ^ f f g h h p~ j{@ ^qq g g g p~ r}@ ^qq g g g p~ rP~@  ^ss t g g p ~ rP~@  ^ f! f" g h# h p$~ j{@  ^ss g g g p%~ r}@  ^ f& f' g h h p(~ j{@ ^ssgggprk m) m" m u* u \+~ vP~@ w, x-yyyyz b{ c c c c c d o | }. ~' ~ / ~0 1~ @ ^2 _3````a b^ c c c c c d o ^ f4 f    5~ {@^ f6 f" g h h p7~ j{@ kll m m m \8~ n}@ 9 : b^ c c c c c d o ^ f; f" g h h p<~ j{@ ^qq g g g p=~ r}@ ^qq g g g p>~ rP~@ ^ss g g g p?~ rP~@^ f@ f g h h pA~ j{@ ^ss g g g pB~ r}@Dl:Hvv`Hvv```v`vvHvvHvvv`Hvv```v ! 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